Article
Heterogeneity of hepatitis C virus genotype 4 strains circulating in south-western France.
The Journal of general virology - 1 Jan 2005
Nicot Florence, Legrand-Abravanel Florence, Sandres-Saune Karine, Boulestin Anne, Dubois Martine, Alric Laurent, Vinel Jean-Pierre, Pasquier Christophe, Izopet Jacques
Abstract excerpt
Hepatitis C virus (HCV) is a major cause of liver disease. Knowledge of HCV variability is crucial for clinical and epidemiological analysis. HCV genotype 4 (HCV-4) has become increasingly prevalent in European countries, including France, in recent years. The present study investigates the heterogeneity of HCV-4 in south-western France by phylogenetic analysis of NS5B sequences from 166 patients. The E2 region...
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