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Article

Higher efavirenz concentrations determine the response to viruses carrying non-nucleoside reverse transcriptase resistance mutations.

AIDS (London, England) - 21 Oct 2004

González de Requena Daniel, Gallego Oscar, Corral Angélica, Jiménez-Nácher Inmaculada, Soriano Vincent

Abstract excerpt

We examined the influence of both efavirenz plasma concentrations and non-nucleoside reverse transcriptase (NNRTI) resistance mutations on the antiviral activity of efavirenz in patients experiencing early virological failure under nevirapine-containing regimens. Up to 41% of patients reach less...

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PMID: 15577634
DOI: 10.1097/00002030-200410210-00017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15577634-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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