Article
Mast cells and vasculature in atopic dermatitis--potential stimulus of neoangiogenesis.
Allergy - 1 Jan 2005
Groneberg D A, Bester C, Grützkau A, Serowka F, Fischer A, Henz B M, Welker P
Abstract excerpt
BACKGROUND: Atopic dermatitis skin lesions are characterized by inflammatory changes and epithelial hyperplasia requiring angiogenesis. As mast cells may participate in this process via bidirectional secretion of tissue-damaging enzymes and pro-angiogenic factors, the present study aimed to assess the occurrence and possible function of mast cells in the papillary dermis and in epidermal layers of atopic...
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