Article
Classification of STR allelic variation using massively parallel sequencing and assessment of flanking region power.
Forensic science international. Genetics - 1 Sept 2020
Devesse Laurence, Davenport Lucinda, Borsuk Lisa, Gettings Katherine, Mason-Buck Gabriella, Vallone Peter M, Syndercombe Court Denise, Ballard David
Abstract excerpt
The application of massively parallel sequencing (MPS) to forensic genetics has led to improvements in multiple aspects of DNA analysis, however, additional complexities are concurrently associated with these advances. In relation to short tandem repeat (STR) typing, the move to sequence rather than length-based methodologies has highlighted the extent to which previous allelic variation was masked - both within...
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