Article
Respiratory syncytial virus deficient in soluble G protein induced an increased proinflammatory response in human lung epithelial cells.
Virology - 20 Dec 2004
Arnold Ralf, König Brigitte, Werchau Hermann, König Wolfgang
Abstract excerpt
Respiratory syncytial virus (RSV) is worldwide the single most important respiratory pathogen in infancy and early childhood. The G glycoprotein of RSV, named attachment protein, is produced by RSV-infected lung epithelial cells in both a membrane-anchored (mG protein) and a soluble form (sG protein) that is secreted by the epithelial cell. Currently, the biological role of the sG protein in primary RSV infection...
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