Article
Genetic diversity of hepatitis B virus strains derived worldwide: genotypes, subgenotypes, and HBsAg subtypes.
Intervirology - 1 Jan 2004
Norder Helene, Couroucé Anne-Marie, Coursaget Pierre, Echevarria José M, Lee Shou-Dong, Mushahwar Isa K, Robertson Betty H, Locarnini Stephen, Magnius Lars O
Abstract excerpt
Sequences of 234 complete genomes and 631 hepatitis B surface antigen genes were used to assess the worldwide diversity of hepatitis B virus (HBV). Apart from the described two subgenotypes each for A and F, also B, C, and D divided into four subgenotypes each in the analysis of complete genomes supported by significant bootstrap values. The subgenotypes of B and C differed in their geographical distribution,...
Topics
- Amino Acid Sequence
- Animals
- Demography
- Genetic Variation
- Genotype
- Hepatitis B virus
- Humans
- Molecular Epidemiology
- Molecular Sequence Data
- Phylogeny
- Sequence Analysis
