Article
[Genetic analysis of X-chromosome neurodegenerative mutants of Drosophila melanogaster induced by ethyl methansulfonate and nitrosoethylurea].
Genetika - 1 Sept 2004
Shcherbata G R, Matiĭtsiv N P, Chernik Ia I, Iatsenko A S, Radysh V V, Kucherenko M M, Maksimiv D V
Abstract excerpt
In a series of Drosophila mutants with changes in the brain structure, some characters (reduced life span, behavioral changes, and neuronal loss in various brain regions) resemble symptoms observed in human patients with neurodegenerative diseases. In addition, similar specific phenotypes shared by different species suggest that common mechanisms underlie degeneration of their nerve cell. This study reports the...
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