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Article

A mutation in a novel ATP-dependent Lon protease gene in a kindred with mild mental retardation.

Neurology - 23 Nov 2004

Higgins Joseph J, Pucilowska Joanna, Lombardi Roni Q, Rooney John P

Abstract excerpt

BACKGROUND: Identifying the genetic factors that contribute to memory and learning is limited by the complexity of brain development and the lack of suitable human models for mild disorders of cognition. METHODS: Previously, a disease locus was mapped for a mild type of nonsyndromic mental retardation (IQ between 50 and 70) to a 4.2-MB interval on chromosome 3p25-pter in a large kindred. The genes and transcripts...

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Identifiers

PMID: 15557513
DOI: 10.1212/01.wnl.0000146196.01316.a2
PMCID: PMC1201536

Genes

CRBN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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