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Article

Structural abnormalities at neuromuscular synapses lacking multiple syntrophin isoforms.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 17 Nov 2004

Adams Marvin E, Kramarcy Neal, Fukuda Taku, Engel Andrew G, Sealock Robert, Froehner Stanley C

Abstract excerpt

The syntrophins are modular adapter proteins that function by recruiting signaling molecules to the cytoskeleton via their direct association with proteins of the dystrophin protein family. We investigated the physiological function of beta2-syntrophin by generating a line of mice lacking this syntrophin isoform. The beta2-syntrophin null mice show no overt phenotype, or muscular dystrophy, and form structurally...

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Identifiers

PMID: 15548643
DOI: 10.1523/JNEUROSCI.3408-04.2004
PMCID: PMC6730292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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