Article
Structural abnormalities at neuromuscular synapses lacking multiple syntrophin isoforms.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 17 Nov 2004
Adams Marvin E, Kramarcy Neal, Fukuda Taku, Engel Andrew G, Sealock Robert, Froehner Stanley C
Abstract excerpt
The syntrophins are modular adapter proteins that function by recruiting signaling molecules to the cytoskeleton via their direct association with proteins of the dystrophin protein family. We investigated the physiological function of beta2-syntrophin by generating a line of mice lacking this sy...
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