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Quantitative Analysis of Circulating Plasma DNA as a Tumor Marker in Thoracic Malignancies

12 Nov 2004

Abstract excerpt

BACKGROUND: Increased plasma DNA has been found in cancer patients and may have potential as a tumor marker. The objectives of this study were to develop a controlled, quantitative PCR (QPCR) assay to measure plasma DNA and then evaluate plasma DNA concentrations as a tumor marker in patients with thoracic malignancies. METHODS: We developed a QPCR assay for DNA, using the human beta-actin gene. Plasma samples...

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Identifiers

PMID: 15539466
DOI: 10.1373/clinchem.2004.039263

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