Article
High-yield expression of recombinant SARS coronavirus nucleocapsid protein in methylotrophic yeast Pichia pastoris.
World journal of gastroenterology - 15 Dec 2004
Liu Ru-Shi, Yang Kun-Yu, Lin Jian, Lin Yi-Wei, Zhang Zhi-Hong, Zhang Jun, Xia Ning-Shao
Abstract excerpt
AIM: Nucleocapsid (N) protein plays an important role in reproduction and pathological reaction of severe acute respiratory syndrome (SARS) coronavirus (SCoV), the antigenicity of the protein is better than spike (S) protein. This study was to find a highly specific and antigenic recombinant SCoV nucleocapsid (rSCoVN) protein, and to provide a basis for further researches on early diagnosis of SARS. METHODS: Full...
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