Article
IGF2 antisense transcript expression in porcine postnatal muscle is affected by a quantitative trait nucleotide in intron 3.
Genomics - 1 Dec 2004
Braunschweig Martin H, Van Laere Anne-Sophie, Buys Nadine, Andersson Leif, Andersson Göran
Abstract excerpt
A paternally expressed quantitative trait locus (QTL) for muscle mass was mapped to the insulin-like growth factor II (IGF2) locus at the distal end of pig chromosome 2p. It was recently demonstrated that a G to A transition at position intron 3-nt 3072 is the quantitative trait nucleotide (QTN) underlying this QTL. In this study we report for the first time the existence of imprinted porcine IGF2 antisense...
Topics
- Animals
- Fetus
- Gene Expression Regulation, Developmental
- Genetic Variation
- Genomic Imprinting
- Genotype
- Insulin-Like Growth Factor II
- Introns
- Liver
- Molecular Sequence Data
- Muscle Development