Article
A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig.
Nature - 23 Oct 2003
Van Laere Anne-Sophie, Nguyen Minh, Braunschweig Martin, Nezer Carine, Collette Catherine, Moreau Laurence, Archibald Alan L, Haley Chris S, Buys Nadine, Tally Michael, Andersson Göran, Georges Michel, Andersson Leif
Abstract excerpt
Most traits and disorders have a multifactorial background indicating that they are controlled by environmental factors as well as an unknown number of quantitative trait loci (QTLs). The identification of mutations underlying QTLs is a challenge because each locus explains only a fraction of the phenotypic variation. A paternally expressed QTL affecting muscle growth, fat deposition and size of the heart in pigs...
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