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Article

Residual activity of mutant androgen receptors explains wolffian duct development in the complete androgen insensitivity syndrome.

The Journal of clinical endocrinology and metabolism - 1 Nov 2004

Hannema Sabine E, Scott Ian S, Hodapp John, Martin Howard, Coleman Nick, Schwabe John W, Hughes Ieuan A

Abstract excerpt

Development of the Wolffian ducts (WD) into epididymides and vasa deferentia is dependent on testosterone. Patients with the complete androgen insensitivity syndrome (CAIS) are therefore not expected to develop these structures. However, WD derivatives have been described in cases of CAIS. It is thought that these may be remnants. This study assesses the degree of WD development in 33 patients with CAIS and...

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Identifiers

PMID: 15531547
DOI: 10.1210/jc.2004-0709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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