Thyroid fetal male microchimerisms in mothers with thyroid disorders: presence of Y-chromosomal immunofluorescence in thyroid-infiltrating lymphocytes is more prevalent in Hashimoto's thyroiditis and Graves' disease than in follicular adenomas.

doi:10.1210/jc.2004-1049

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Article

Thyroid fetal male microchimerisms in mothers with thyroid disorders: presence of Y-chromosomal immunofluorescence in thyroid-infiltrating lymphocytes is more prevalent in Hashimoto's thyroiditis and Graves' disease than in follicular adenomas.

The Journal of clinical endocrinology and metabolism - 1 Nov 2004

Renné Christoph, Ramos Lopez Elizabeth, Steimle-Grauer Susanne A, Ziolkowski Piotr, Pani Michael A, Luther Christina, Holzer Katharina, Encke Albrecht, Wahl Robert A, Bechstein Wolf O, Usadel Klaus H, Hansmann Martin-Leo, Badenhoop Klaus

Abstract excerpt

The presence of fetal cells in a maternal compartment is defined as fetal-maternal microchimerism, which has been detected in thyroids of mothers suffering from autoimmunity. We analyzed the immunohistology of paraffin-embedded thyroid specimen taken at surgery from 49 women with Hashimoto's thyroiditis (n = 25), Graves' disease (n = 15), or nodular or diffuse follicular adenomas (n = 9), whose childbirth history...

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PMID: 15531546
DOI: 10.1210/jc.2004-1049

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