Article
[Polymorphism of the gene for vitamin D receptor, bone mass, and bone turnover in women with postmenopausal osteoporosis].
Revista clinica espanola - 1 Apr 2000
Fontova Garrofé R, Gutiérrez Fornés C, Broch Montané M, Aguilar Crespillo C, Pujol del Pozo A, Vendrell Ortega J, Richart Jurado C
Abstract excerpt
OBJECTIVE: To analyze which genotypes of vitamin D receptor (VDR) are associated with the loss or maintenance of bone mass among spanish postmenopausal women. MATERIAL AND METHODS: A total of 105 women with postmenopausal osteoporosis and 51 postmenopausal women without osteoporosis (control group), diagnosed with bone densitometry (DEXA) were included in the study. The genetic locus was analyzed with RFLP by...
Topics
- Bone Density
- Bone Remodeling
- Case-Control Studies
- Female
- Genotype
- Humans
- Middle Aged
- Osteoporosis, Postmenopausal
- Polymorphism, Restriction Fragment Length
- Receptors, Calcitriol
