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Article

No evidence of maternal cell colonization in reverted liver nodules of tyrosinemia type I patients.

Gastroenterology - 1 Nov 2004

Bergeron Anne, Lettre Francine, Russo Pierre, Morissette Jean, Tanguay Robert M

Abstract excerpt

BACKGROUND AND AIMS: Hereditary tyrosinemia type I (HTI) is a recessively inherited disease caused by a deficiency of fumarylacetoacetate hydrolase (FAH), the last enzyme of the tyrosine catabolic pathway. The mosaic pattern of FAH expression observed in the livers of >85% of studied patients was shown to result from the correction of the mutation in one of the FAH alleles. Bilateral cell trafficking can occur...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15521007
DOI: 10.1053/j.gastro.2004.08.013

Genes

FAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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