Article
Topogenesis of carboxylesterases: a rat liver isoenzyme ending in -HTEHT-COOH is a secreted protein.
Biochemical and biophysical research communications - 16 Mar 1992
Robbi M, Beaufay H
Abstract excerpt
We have cloned a rat liver cDNA that encodes a carboxylesterase isoenzyme, as revealed by immunoprecipitation, cytochemical staining and inhibition by bis-p-nitrophenylphosphate of the product expressed in transfected COS cells. The predicted polypeptide ends in -HTEHT-COOH. The product is secreted by COS cells with a half-time of about 1 hour, after maturation of oligosaccharide chains in the Golgi complex. A...
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