[The expression profiles of human chromosome 21 orthologues in mouse M II oocyte].

Abstract excerpt

OBJECTIVE: To analyse the expression profile of orthologues of human chromosome 21 (HC21) in mouse M II oocytes, and to discuss the relationship between this expression profile and early embryonic development and further to find the possible reasons of DS phenotypes genesis. METHODS: cDNA array and Global RT-PCR methods were used to analyse and identify the expression profile of 93 HC21 orthologues in mouse M II...

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