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Investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratories

23 Oct 2004

Abstract excerpt

JC virus (JCV), BK virus (BKV) and simian virus 40 (SV40) may be associated with human brain tumors. These polyomaviruses have been shown to induce brain tumors in experimentally infected animals. Several studies have found polyomavirus genomic sequences in human brain tumor tissues by using polymerase chain reaction (PCR), while others have not. Inconsistencies in previous findings may be due in part to small...

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PMID: 15499616
DOI: 10.1002/ijc.20641

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