Article
Regulation of FlbD activity by flagellum assembly is accomplished through direct interaction with the trans-acting factor, FliX.
Molecular microbiology - 1 Nov 2004
Muir Rachel E, Gober James W
Abstract excerpt
The temporal and spatial transcription of late flagellar genes in Caulobacter crescentus is regulated by the sigma54 transcriptional activator, FlbD. One requirement for FlbD activity is the assembly of a structure encoded by early, class II flagellar genes. In this report, we show that the trans-acting factor FliX predominantly functions as a negative regulator of FlbD activity in the absence of the class...
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