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Article

The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis.

Human genetics - 1 Nov 2004

Ritzka Margit, Stanke Frauke, Jansen Silke, Gruber Achim D, Pusch Larissa, Woelfl Stefan, Veeze Henk J, Halley Dicky J, Tümmler Burkhard

Abstract excerpt

To determine whether the CLCA gene family of calcium-activated chloride channels is a modulator of the basic defect of cystic fibrosis (CF), an association study was performed with polymorphic microsatellite markers covering a 40-Mbp region spanning the CLCA gene locus on human chromosome 1p in CF patients displaying CF transmembrane conductance regulator (CFTR)-independent residual chloride conductance in...

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Identifiers

PMID: 15490240
DOI: 10.1007/s00439-004-1190-y

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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