Article
Differential-display PCR of peripheral blood for biomarker discovery in chronic fatigue syndrome.
Journal of molecular medicine (Berlin, Germany) - 1 Nov 2004
Steinau Martin, Unger Elizabeth R, Vernon Suzanne D, Jones James F, Rajeevan Mangalathu S
Abstract excerpt
We used differential-display PCR of peripheral blood mononuclear cells (PBMCs) to search for candidate biomarkers for chronic fatigue syndrome (CFS). PBMCs were collected from a subject with CFS and an age- and sex-matched control before and 24 h after exercise. RNA expression profiles were generated using 46 primer combinations, and the similarity between the individuals was striking. Differentially expressed...
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