Article
Autism as a paradigmatic complex genetic disorder.
Annual review of genomics and human genetics - 1 Jan 2004
Veenstra-Vanderweele Jeremy, Christian Susan L, Cook Edwin H
Abstract excerpt
Autism is one of the most heritable complex disorders, with compelling evidence for genetic factors and little or no support for environmental influence. The estimated prevalence of autism has increased since molecular genetic studies began, owing to loosening of diagnostic criteria and, more importantly, to more complete ascertainment strategies. This has led to a reduction in the sibling relative risk, but...
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