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A temperature-sensitive dcw1 mutant of Saccharomyces cerevisiae is cell cycle arrested with small buds which have aberrant cell walls.

Eukaryotic cell - 1 Oct 2004

Kitagaki Hiroshi, Ito Kiyoshi, Shimoi Hitoshi

Abstract excerpt

Dcw1p and Dfg5p in Saccharomyces cerevisiae are homologous proteins that were previously shown to be involved in cell wall biogenesis and to be essential for growth. Dcw1p was found to be a glycosylphosphatidylinositol-anchored membrane protein. To investigate the roles of these proteins in cell wall biogenesis and cell growth, we constructed mutant alleles of DCW1 by random mutagenesis, introduced them into a...

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Identifiers

PMID: 15470258
DOI: 10.1128/EC.3.5.1297-1306.2004
PMCID: PMC522616

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