Article
Effects of the G190A substitution of HIV reverse transcriptase on phenotypic susceptibility of patient isolates to delavirdine.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Nov 2004
Uhlmann Erik J, Tebas Pablo, Storch Gregory A, Powderly William G, Lie Yolanda S, Whitcomb Jeannette M, Hellmann Nicholas S, Arens Max Q
Abstract excerpt
BACKGROUND: Cross resistance is common among the non-nucleoside reverse transcriptase inhibitors (NNRTIs). G190A appears in 5-15% of the patients treated with nevirapine or efavirenz who develop clinical resistance. OBJECTIVES: In this study we investigated the effect of G190A and other NNRTI sub...
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