Article
Plasma levels of alpha-melanotropin and ACTH-like immunoreactivities do not vary by season or skin type in women from southern and central Europe.
Neuropeptides - 1 Oct 2004
Pichler Robert, Crespillo Carmen, Maschek Wilma, Esteva Isabel, Soriguer Federico, Sfetsos Konstantin, Auböck Josef
Abstract excerpt
Melanotropins (MSH) are involved in tanning by stimulating melanocytes via the activation of the melanocortin-1 receptor to melanin production. Its main site of production is the pituitary gland, but alpha-MSH and related ACTH peptides are produced at other sites, including the skin. It has been hypothesized that systemic levels of alpha-MSH are controlled by a varying UV radiation (UVR) exposure. A seasonal...
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