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Permanent Neonatal Diabetes due to Mutations in <i>KCNJ11</i> Encoding Kir6.2

1 Oct 2004

Abstract excerpt

Permanent neonatal diabetes (PND) can be caused by mutations in the transcription factors insulin promoter factor (IPF)-1, eukaryotic translation initiation factor-2alpha kinase 3 (EIF2AK3), and forkhead box-P3 and in key components of insulin secretion: glucokinase (GCK) and the ATP-sensitive K(+) channel subunit Kir6.2. We sequenced the gene encoding Kir6.2 (KCNJ11) in 11 probands with GCK-negative PND....

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Identifiers

PMID: 15448106
DOI: 10.2337/diabetes.53.10.2713

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Permanent Neonatal Diabetes due to Mutations in <i>KCNJ11</i> Encoding Kir6.2PMID 15448106Read ↗

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