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RNAs Are Packaged into Human Cytomegalovirus Virions in Proportion to Their Intracellular Concentration

14 Sept 2004

Abstract excerpt

The assembly of human cytomegalovirus (HCMV) virions is a complex process and involves the incorporation of viral transcripts. These RNAs are delivered to the newly infected cells and have the potential to be translated in the absence of HCMV gene expression. We have quantified the relative amount of RNAs in HCMV virions and infected cells with real-time reverse transcription-PCR and observed that viral and...

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PMID: 15367605
DOI: 10.1128/jvi.78.19.10390-10398.2004

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