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[KatG Ser3 15Thr mutation as the main reason of isoniazid resistance in Mycobacterium tuberculosis isolated in the Novosibirsk and Kemerovo Regions].

Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Jan 2004

Voronina E N, Vikhrova M A, Khrapov E A, Kinsht V N, Norkina O V, Gorbunova E V, Shabaldin A V, Glushkov A N, Krasnov V A, Filipenko M L

Abstract excerpt

KatG Ser3 15Thr mutation is one of the main reasons of resistance to isoniazid in Mycobacterium tuberculosis isolates. The frequency rate of the above mutation among isoniazid-resistant isolates made 94% in Novosibirsk Region and 93% in Kemerovo Region. The use of PCR-restriction fragment length polymorphism (PCR-RFLP) can be regarded as an adequate method for rapid screening of isoniazid resistance in...

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PMID: 15354935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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