Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Pathogenesis and treatment of refractory gastroesophageal reflux disease in Japanese patients].

Nihon rinsho. Japanese journal of clinical medicine - 1 Aug 2004

Fujiwara Yasuhiro, Higuchi Kazuhide, Yamamori Kazuki, Watanabe Yoko, Shiba Masatsugu, Watanabe Toshio, Tominaga Kazunari, Oshitani Nobuhide, Matsumoto Takayuki, Arakawa Tetsuo

Abstract excerpt

Prevalence of refractory gastroesophageal reflux disease (GERD) defined as a patient who have persistent GERD symptoms during treatment with proton pump inhibitor (PPI) is rare in Japanese patinets. Pathogenesis of refractory GERD is associated with several factors including dysfunction of esophageal motility, presence of severe hiatal hernia, complication such as stricture and short esophagus, extensive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 CYP2C19
Share to Esophagus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastric Acid

Share to Gastroesophageal Reflux

Share to Life Style

Share to Mixed Function Oxygenases

Share to Monitoring, Physiologic

Share to Proton Pump Inhibitors

Source

Identifiers

PMID: 15344542

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Pathogenesis and treatment of refractory gastroesophageal reflux disease in Japanese patients].PMID 15344542Read ↗

[Underlying Mechanisms and Management of Refractory Gastroesophageal Reflux Disease].Semantic proximity Read ↗

[Test of refractory gastroesophageal reflux disease].Semantic proximity Read ↗

Optimal management of severe symptomatic gastroesophageal reflux disease.Semantic proximity Read ↗

Refractory ulcer of reconstructed gastric tube after esophagectomy: a case report.Semantic proximity Read ↗

Proton pump inhibitors and recurrent bleeding in peptic ulcer disease.Semantic proximity Read ↗

A multicentre randomised trial to compare the efficacy of omeprazole versus rabeprazole in early symptom relief in patients with reflux esophagitis.Semantic proximity Read ↗

A review of medical therapy for proton pump inhibitor nonresponsive gastroesophageal reflux disease.Semantic proximity Read ↗

Delayed Intrathoracic Gastric Perforation after G-POEM for Treating Post-Operative Refractory Gastroparesis：A Case Report and Review of LiteratureSemantic proximity Read ↗

Esomeprazole inhibits the pentagastrin-stimulated secretion of gastric acid in healthy Japanese volunteers.Semantic proximity Read ↗

Safety and short-term efficacy of GERD patients with ineffective esophageal motility treated with RefluxStop™ device implantation – a multicentric observational studySemantic proximity Read ↗

Characteristics of refractory gastroesophageal reflux disease (GERD) symptoms -is switching proton pump inhibitors based on the patient's CYP2C19 genotype an effective management strategy?Semantic proximity Read ↗

Efficacy of proton pump inhibitor on nighttime reflux symptoms and associated sleep disturbances in patients with gastroesophageal reflux disease: A real-world study in northern ChinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.