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Article

Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia.

American journal of human genetics - 1 Oct 2004

Duan Jubao, Martinez Maria, Sanders Alan R, Hou Cuiping, Saitou Naruya, Kitano Takashi, Mowry Bryan J, Crowe Raymond R, Silverman Jeremy M, Levinson Douglas F, Gejman Pablo V

Abstract excerpt

Several linkage studies across multiple population groups provide convergent support for a susceptibility locus for schizophrenia--and, more recently, for bipolar disorder--on chromosome 6q13-q26. We genotyped 192 European-ancestry and African American (AA) pedigrees with schizophrenia from samples that previously showed linkage evidence to 6q13-q26, focusing on the MOXD1-STX7-TRARs gene cluster at 6q23.2, which...

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Source

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Identifiers

PMID: 15329799
DOI: 10.1086/424887
PMCID: PMC1182049

Genes

MOXD1
STX7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia.PMID 15329799Read ↗

Molecular Variants in Human Trace Amine-Associated Receptors and Their Implications in Mental and Metabolic Disorders.Semantic proximity Read ↗

Association of the trace amine associated receptor 6 (TAAR6) gene with schizophrenia and bipolar disorder in a Korean case control sample.Semantic proximity Read ↗

Possible role of rare variants in Trace amine associated receptor 1 in schizophrenia.Semantic proximity Read ↗

No association of haplotype-tagging SNPs in TRAR4 with schizophrenia in Japanese patients.Semantic proximity Read ↗

A region of 35 kb containing the trace amine associate receptor 6 (TAAR6) gene is associated with schizophrenia in the Irish study of high-density schizophrenia families.Semantic proximity Read ↗

TAAR6 variation effect on clinic presentation and outcome in a sample of schizophrenic in-patients: an open label study.Semantic proximity Read ↗

No support for an association with TAAR6 and schizophrenia in a linked population of European ancestry.Semantic proximity Read ↗

The trace amine receptor 4 gene is not associated with schizophrenia in a sample linked to chromosome 6q23.Semantic proximity Read ↗

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The trace amine associated receptor (TAAR6) gene is not associated with schizophrenia in the Irish Case-Control Study of Schizophrenia (ICCSS) sample.Semantic proximity Read ↗

A genetic locus in 7p12.2 associated with treatment resistant schizophrenia.Semantic proximity Read ↗

Trace amine associated receptor 1: Predicted effects of single nucleotide variants on structure-function in geographically diverse populationsSemantic proximity Read ↗

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