Article
Pulmonary clearance of Moraxella catarrhalis in an animal model.
The Journal of infectious diseases - 1 Apr 1992
Unhanand M, Maciver I, Ramilo O, Arencibia-Mireles O, Argyle J C, McCracken G H, Hansen E J
Abstract excerpt
The virulence mechanisms of Moraxella catarrhalis that are involved in producing pulmonary infection are unknown. A well-characterized murine model was used to study the pulmonary clearance of M. catarrhalis and analyze the histopathologic changes and the role of phagocytic cells in the infected lungs. Ten strains of M. catarrhalis from various isolation sites were evaluated for their ability to resist pulmonary...
Topics
- Animals
- Antigens, Bacterial
- Bacterial Outer Membrane Proteins
- Bronchoalveolar Lavage Fluid
- Cell Count
- Disease Models, Animal
- Electrophoresis, Polyacrylamide Gel
- Female
- Lipopolysaccharides
- Lung
- Macrophages, Alveolar