Article
Transforming growth factor-beta1, interleukin-10 and interferon-gamma cytokine polymorphisms in patients with hereditary, familial and sporadic chronic pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Jan 2004
Schneider Alexander, Barmada M Michael, Slivka Adam, Martin John A, Whitcomb David C
Abstract excerpt
BACKGROUND: The genetic influence is undefined in about 40% of patients with hereditary and familial pancreatitis and in the majority of patients with sporadic chronic pancreatitis. The pathophysiological mechanisms underlying the progression from acute to chronic pancreatitis have not been clarified. Cytokines participate in the immunological progression of pancreatic inflammation and may play an important role...
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