Article
Prevalence of Fabry disease in female patients with late-onset hypertrophic cardiomyopathy.
Circulation - 31 Aug 2004
Chimenti Cristina, Pieroni Maurizio, Morgante Emanuela, Antuzzi Daniela, Russo Andrea, Russo Matteo Antonio, Maseri Attilio, Frustaci Andrea
Abstract excerpt
BACKGROUND: Fabry disease (FD) has been recognized as the cause of left ventricular hypertrophy in 6% of men with late-onset hypertrophic cardiomyopathy (HCM). Although FD is considered a recessive X-linked disorder, affected women are increasingly reported. The aim of our study was to determine the prevalence of FD in female patients with HCM. METHODS AND RESULTS: Thirty-four consecutive women (mean age,...
Topics
- Adult
- Age of Onset
- Aged
- Biopsy
- Cardiomyopathy, Hypertrophic
- DNA Mutational Analysis
- Electrocardiography
- Endocardium
- Fabry Disease
- Female
- Genotype