Article
Comparison of mitochondrial cytochrome oxidase 1 DNA sequences from Necator americanus hookworms maintained for 100 generations in golden hamsters (Mesocricetus auratus) and hookworms from natural human infections.
Acta tropica - 1 Sept 2004
Li Tie-Hua, Guo Xiang-Rong, Xue Jian, Hu Ling, Qiang Hui-Qin, Xue Hai-Chou, Bin Zhan, Hawdon John M, Xiao Shu-Hua
Abstract excerpt
The human hookworm Necator americanus was maintained through one hundred generations in the golden hamsters. The strain is now routinely maintained in laboratory hamsters through serial passage, and is the laboratory strain of choice for vaccine studies. Comparison of the mitochondrial cytochrome oxidase 1 (cox-1) sequences was shown previously to be useful for comparing the genetic structure of populations of N....
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