Article
Comparative whole-genome analysis of virulent and avirulent strains of Porphyromonas gingivalis.
Journal of bacteriology - 1 Aug 2004
Chen Tsute, Hosogi Yumiko, Nishikawa Kiyoshi, Abbey Kevin, Fleischmann Robert D, Walling Jennifer, Duncan Margaret J
Abstract excerpt
We used Porphyromonas gingivalis gene microarrays to compare the total gene contents of the virulent strain W83 and the avirulent type strain, ATCC 33277. Signal ratios and scatter plots indicated that the chromosomes were very similar, with approximately 93% of the predicted genes in common, while at least 7% of them showed very low or no signals in ATCC 33277. Verification of the array results by PCR indicated...
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