Article
Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition.
The New England journal of medicine - 29 Jul 2004
Kriege Mieke, Brekelmans Cecile T M, Boetes Carla, Besnard Peter E, Zonderland Harmine M, Obdeijn Inge Marie, Manoliu Radu A, Kok Theo, Peterse Hans, Tilanus-Linthorst Madeleine M A, Muller Sara H, Meijer Sybren, Oosterwijk Jan C, Beex Louk V A M, Tollenaar Rob A E M, de Koning Harry J, Rutgers Emiel J T, Klijn Jan G M
Abstract excerpt
BACKGROUND: The value of regular surveillance for breast cancer in women with a genetic or familial predisposition to breast cancer is currently unproven. We compared the efficacy of magnetic resonance imaging (MRI) with that of mammography for screening in this group of high-risk women. METHODS: Women who had a cumulative lifetime risk of breast cancer of 15 percent or more were screened every six months with a...
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