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Article

Molecular analysis of common aldolase B alleles for hereditary fructose intolerance in North Americans.

Biochemical medicine and metabolic biology - 1 Aug 1992

Tolan D R, Brooks C C

Abstract excerpt

The diagnosis of hereditary fructose intolerance (HFI) presents a difficult challenge that often involves procedures of high risk to the patient. A relatively noninvasive method that involves molecular analysis of common alleles would offer a decided advantage. The molecular defects in the aldolase B gene were studied in 31 HFI subjects (23 pedigrees, 47 apparently independent alleles) from the United States and...

Topics

Alleles
Base Sequence
Fructose Intolerance
Fructose-Bisphosphate Aldolase
Gene Frequency
Humans
Molecular Sequence Data
North America

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1524867
DOI: 10.1016/0885-4505(92)90043-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1524867-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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