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Article

Screening for hereditary fructose intolerance mutations by reverse dot-blot.

Molecular and cellular probes - 1 Feb 1999

Lau J, Tolan D R

Abstract excerpt

An assay is described which is useful for genetic screening of the two most prevalent mutations that cause hereditary fructose intolerance (HFI). Both mutations lie within exon 5 of the aldolase B gene. Amplification of exon 5 from genomic DNA isolated from peripheral lymphocytes using biotinylated aldolase B-specific primers yields a biotin-tagged probe. This probe is hybridized to complementary poly(dT)-tailed...

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Source

Identifiers

PMID: 10024431
DOI: 10.1006/mcpr.1998.0208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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