Article
Global gene expression in Staphylococcus aureus biofilms.
Journal of bacteriology - 1 Jul 2004
Beenken Karen E, Dunman Paul M, McAleese Fionnuala, Macapagal Daphne, Murphy Ellen, Projan Steven J, Blevins Jon S, Smeltzer Mark S
Abstract excerpt
We previously demonstrated that mutation of the staphylococcal accessory regulator (sarA) in a clinical isolate of Staphylococcus aureus (UAMS-1) results in an impaired capacity to form a biofilm in vitro (K. E. Beenken, J. S. Blevins, and M. S. Smeltzer, Infect. Immun. 71:4206-4211, 2003). In this report, we used a murine model of catheter-based biofilm formation to demonstrate that a UAMS-1 sarA mutant also has...
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