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Article

Differential expression and antibacterial activity of epididymis protein 2 isoforms in the male reproductive tract of human and rhesus monkey (Macaca mulatta).

Biology of reproduction - 1 Nov 2004

Avellar Maria Christina W, Honda Luciana, Hamil Katherine G, Yenugu Suresh, Grossman Gail, Petrusz Peter, French Frank S, Hall Susan H

Abstract excerpt

The epididymis protein 2 (EP2) gene, the fusion of two ancestral beta-defensin genes, is highly expressed in the epididymis and subject to species-specific regulation at the levels of promoter selection, transcription, and mRNA splicing. EP2 mRNA expression is also androgen dependent, and at least two of the secreted proteins bind spermatozoa. Alternative splicing produces more than 17 different EP2 mRNA...

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PMID: 15229135
DOI: 10.1095/biolreprod.104.031740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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