Characterization of the Campylobacter fetus sapA promoter: evidence that the sapA promoter is deleted in spontaneous mutant strains.

Abstract excerpt

Wild-type Campylobacter fetus cells possess S-layer proteins (S+ phenotype), whereas after laboratory passage, spontaneous stable mutants that do not express these proteins (S- phenotype) arise. To determine the molecular mechanisms by which C. fetus changes to the S- phenotype, we studied wild-t...

Topics

• Antigens, Bacterial
• Bacterial Proteins
• Base Sequence
• Blotting, Southern
• Campylobacter fetus
• Chromosome Mapping
• Cloning, Molecular
• Gene Expression Regulation, Bacterial
• Genetic Variation
• Membrane Glycoproteins
• Molecular Sequence Data
• Multigene Family
• Mutagenesis
• Phenotype
• Polymerase Chain Reaction
• Promoter Regions, Genetic