Article
Novel hepatitis B virus genotype a subtyping assay that distinguishes subtype Aa from Ae and its application in epidemiological studies.
Journal of virology - 1 Jul 2004
Hasegawa Izumi, Tanaka Yasuhito, Kramvis Anna, Kato Takanobu, Sugauchi Fuminaka, Acharya Subrat K, Orito Etsuro, Ueda Ryuzo, Kew Michael C, Mizokami Masashi
Abstract excerpt
The eight genotypes of hepatitis B virus (HBV) have different geographical distributions, virological characteristics, and clinical manifestations. A unique subtype of HBV genotype A (HBV/A) was reported in sub-Saharan Africa, raising the possibility that patients infected with this subtype (HBV/Aa ["a" for African and Asian]) may have different clinical outcomes than other HBV/A isolates (HBV/Ae ["e" for...
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