Article
Isolation of multiple TT virus genotypes from spleen biopsy tissue from a Hodgkin's disease patient: genome reorganization and diversity in the hypervariable region.
Journal of virology - 1 Jul 2004
Jelcic Ilijas, Hotz-Wagenblatt Agnes, Hunziker Andreas, Zur Hausen Harald, de Villiers Ethel-Michele
Abstract excerpt
We report the isolation of 24 novel genotypes of TT viruses from a surgically removed spleen of a patient with Hodgkin's disease. The sequence analysis of our 24 isolates revealed the remarkable heterogeneity of TT virus isolates not only from the same patient but also from the same biopsy material. These isolates belong to four phylogenetic groups of TT viruses. Nucleotide sequence analyses revealed five...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
