Article
No association of C677T methylenetetrahydrofolate reductase and an endothelial nitric oxide synthase polymorphism with recurrent pregnancy loss.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Jul 2004
Makino Aiko, Nakanishi Tamao, Sugiura-Ogasawara Mayumi, Ozaki Yasuhiko, Suzumori Nobuhiro, Suzumori Kaoru
Abstract excerpt
PROBLEM: It is controversial whether polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and the endothelial nitric oxide synthase (eNOS) are associated with recurrent pregnancy loss. METHOD OF STUDY: We studied the frequency of the C677T polymorphism of MTHFR and a eNOS gene polymorphism, as well as the plasma levels of homocysteine and NO, in 85 cases with a history of two or more unexplained embryonal...
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