Article
Sample size requirements for clinical trials of isolated systolic hypertension.
Clinical and experimental pharmacology & physiology - 1 May 1992
Silagy C A, McNeil J J, McGrath B P
Abstract excerpt
1. This study investigated components of blood pressure variability in elderly subjects with isolated systolic hypertension (ISH) using both ambulatory blood pressure monitoring (ABPM) and casual clinic blood pressure measurement. These were then used to determine sample size requirements for clinical trials of different designs. 2. Eleven elderly subjects not receiving antihypertensive medication were seen on...
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