Study of host-pathogen interactions to identify sustainable vaccine strategies to Marek's disease.

doi:10.1016/j.vetimm.2004.04.009

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Article

Study of host-pathogen interactions to identify sustainable vaccine strategies to Marek's disease.

Veterinary immunology and immunopathology - 1 Aug 2004

Baaten B J G, Butter C, Davison T F

Abstract excerpt

Marek's disease virus is a highly cell-associated, lymphotropic alpha-herpesvirus that causes paralysis and neoplastic disease in chickens. The disease has been contained by vaccination with attenuated viruses and provides the first evidence for a malignant cancer being controlled by an antiviral vaccine. Marek's disease pathogenesis is complex, involving cytolytic and latent infection of lymphoid cells and...

Topics

Animals
Antibody Formation
Chickens
Cytokines
Genetic Predisposition to Disease
Herpesvirus 2, Gallid
Immunity, Cellular
Marek Disease
Marek Disease Vaccines
Vaccination

Source

Open in PubMed

Identifiers

PMID: 15207454
DOI: 10.1016/j.vetimm.2004.04.009

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