Article
Modulation of Env content in virions of simian immunodeficiency virus: correlation with cell surface expression and virion infectivity.
Journal of virology - 1 Jul 2004
Yuste Eloísa, Reeves Jacqueline D, Doms Robert W, Desrosiers Ronald C
Abstract excerpt
Specific mutations were created in the cytoplasmic domain of the gp41 transmembrane protein of simian immunodeficiency virus strain 239 (SIV239). The resultant strains included a mutant in which Env residue 767 was changed to a stop codon, a double mutant in which positions 738 and 739 were changed to stop codons, another mutant in which a prominent endocytosis motif was changed from YRPV to GRPV by the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
