Article
Overview of treatment of hepatitis B: key approaches and clinical challenges.
Seminars in liver disease - 1 Jan 2004
Perrillo Robert P
Abstract excerpt
The development of nucleoside analogues has been a major advance in the treatment of hepatitis B; however, prolonged monotherapy is associated with drug resistance. Currently, no data in humans indicate that a combination of nucleoside analogues leads to enhanced efficacy. New nucleoside analogues with greater inhibitory effects on hepatitis B virus (HBV) replication being developed could prove to be more...
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